AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Protein Crowding within the Postsynaptic Density Can Impede the Escape of Membrane Proteins.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Li TP; Song Y; MacGillavry HD; Blanpied TA; Raghavachari S
J. Neurosci., 2016


Table 1.

Simulation parameters

Value Study
PSD-95 radius 2.5 nm Chen et al. (2008)
NMDAR radius 8 nm Chen et al. (2008)
Adhesion molecules, radii 3-8 nm This worka
Other immobile proteins, radii 5-10 nm This worka
NMDAR number 20 Cheng et al. (2006)
Adhesion molecule number 48 Cheng et al. (2006)
Other immobile protein number 15 Cheng et al. (2006)
Diameter of PSD 140-400 nm MacGillavry et al. (2013)
AMPAR number within a synapse 100 Matsuzaki et al. (2001)
AMPAR diffusion constant 0.2 μm2/s Ehlers et al. (2007)
  • aRadii of assumed unstructured conformations were deduced from total counts of amino acids based on the radius of gyration estimates of peptide chains by Kohn et al. (2004).


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source